Pac-12 Football Picks: After a 55-Year Wait, Can Cal Get It Done vs. Notre Dame?

The final weekend of non-conference play is on Saturday. 11 Pac-12 teams are playing. Cal plays at South Bend, Indiana, in the first meeting between the two programs since 1967. Unbeaten BYU visits Oregon, Michigan State travels to Seattle to take on Washington, and Fresno State goes to the L.A. Coliseum to play USC.

Jeff and Jake are picking Cal to beat Notre Dame.

Jeff and Jake are Pac-12 football picks.

After a 55-year wait, Cal will play against Notre Dame.

South Alabama is favored to beat UCLA. The Bruins have scored 45 points in each of their first two games.

Cal is favored by 11 points against Notre Dame. The game is the first in 55 years.

BYU is coming off a win over Baylor. Oregon scored 70 points against Eastern Washington.

Colorado is a plus-28 favorite at Minnesota. Colorado is 126th in scoring. Minnesota's best team so far this season.

Colorado State is a plus-17 favorite against Washington State. The Cougars are 2-0. Colorado State has given up 85 points in two losses.

Michigan State is favored by 3.5 points at Washington. The game will be played at Husky Stadium.

MONTANA STATE (no line) plays at OREGON State (5 p.m. Pacific) on Pac-12 Networks. Big Sky's Montana State Bobcats are averaging 51.5 points and 564 yards per game. Montana's last Pac 12 game was a 31-0 loss at Washington State five years ago.

San Diego State is favored by 21 points at Utah. The Aztecs lost to Arizona by 18 points in San Diego.

Jake Haener and Jeff are picking Fresno State to beat USC. Nikko Remigio has back-to-back 100-yard receiving games for Fresno. Jake Haeners and Jeffrey are going to pick USC to win.

North Dakota State is the No. 1-ranked FCS team. Arizona is a team that has no record against the Bison.

Arizona State is favored to beat Eastern Michigan. Eastern Miserich lost 55-0 at Arizona in 1988.

After a 55-year wait, Cal will play Notre Dame.