Panthers vs. Giants Picks, Predictions NFL Week 2: Surging G-Men Host Carolina as Slim Favorites

The New York Giants beat the AFC South champion Tennessee Titans last week. The Giants are looking for their first back-to-back wins since midway through the 2020 season. Carolina Panthers suffered a narrow loss to the Cleveland Browns in their home opener.

Panthers vs. Giants is a Sunday at 1 p.m. ET at MetLife Stadium in East Rutherford, NJ. The weather is 82 degrees, 10% chance of precipitation, 11-mph winds.

The Panthers are 1.5-point favorites against the Giants. The Panthers have received 65% of the bets and 67% on the spread.

Panthers vs. Giants is a game on Sunday. The spread is 1.5 points. Over/Under is 43. 5 points, and the winner is Saquon Barkley vs Christian McCaffrey rushing yards.

Giants host Carolina Panthers in NFL Week 2. Giants are favored by 1.5 points. Over/Under is 43.

Giants are the underdogs at 1.5 (-112) against the AFC's top-seeded team from 2021. The Giants' impressive second-half comeback in Week 1 would have been unthinkable a year ago.

Injuries to the Giants' secondary should allow Mayfield to enjoy more success than he did in last week’s grudge match against the Browns. Carolina's defense will have its hands full against a New York ground game that steamrolled the Titans for 238 yards last weekend.

Giants running back Saquon Barkley is energized after racking up 164 rushing yards, a touchdown and the game-winning two-point conversion in last weekend's win. Christian McCaffrey was limited to just 33 rushingyards on 10 carries last week.

Panthers vs. Giants is a game in the NFL Week 2.

Panthers vs. Giants is a game on 9/15/2022 at 4:23 p.m. ET.