Rams vs. Cardinals betting odds and picks against the spread

The Rams are playing against the Arizona Cardinals on Sunday. The Rams need to win to have any chance of winning the 2022 season.

Arizona Cardinals are the underdogs at Rams (-1 1/2, 41). Rams beat the Cardinals earlier in the season, but they have a 1-4 record since then. Matthew Stafford is in concussion protocol. Cardinals have the worst defense in NFL by dropback success rate. Kyler Murray is also injured. Cardinals can't run the ball and they blitz at the second-highest rate in league. They have allowed 212 more yards after the catch than any other team. Rams have been terrific against the run but have struggled in pass defense. The Rams are 24th in dropbacks success percentage. Arizona has the third-worst dropdown success ratio.

Rams vs. Cardinals is a six-point teaser.