San Francisco 49ers: 4 bold predictions for Week 18 vs. Cardinals

The San Francisco 49ers are on a nine-game winning streak. They need to beat the Arizona Cardinals to secure the No. 1 seed in the NFC for the playoffs. The 49er's quarterback Brock Purdy is the third-stringer due to an injury to Jimmy Garoppolo. The team defeated the Raiders in their last game. Their next game is at home against the Cardinals.

Nick Bosa is the frontrunner for the award for best edge rusher. He is also the favorite to win his first Defensive Player of the Year award. Bona is currently leading the NFL with 17.5 sacks this season.

Brandon Aiyuk had a good game in the 49ers' win over the Raiders. He had nine receptions for 101 yards and a touchdown. It was his first 100-yard receiving game of the season. Aiiyuk has 74 receptions and 8 touchdowns this season and will be a key player for the team when they face the Cardinals in their final game. Christian McCaffrey and Deebo Samuel are questionable for this game and Aiyik should be Brock Purdy's No. 1 target.

Brock Purdy tied the team record for touchdown passes by a rookie with 10 for the season. He completed 6-of-10 passes for 113 yards on the final two drives of the game. Purdys finished the match with 284 yards, two touchdowns and one interception.

The 49ers are the hottest team in the NFL. They should win their tenth game in a row. The 49er's have the opportunity to claim the No. 1 seed in NFC and a first-round bye. However, the Eagles and Giants are expected to go all-out against each other.