Seattle Mariners at Cleveland Guardians odds, picks and predictions

The Seattle Guardians (2-5) open a 3-game series against the Cleveland Guardians (5-2) Friday afternoon. First pitch for the Guardians' season opener at Progressive Field is scheduled for 4:10 p.m. ET. Let's analyze BetMGM Sportsbook's lines around the Mariners vs. Guardiansodds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 3-1

The Guardians lost 3-0 at the Mariners Opening Day but rebounded by taking the final 3 games of that opening series, outscoring Seattle 17-9. Cleveland then went to Oakland and took 2 of 3, so it has won 5 of 6 since dropping the season opener.

The Mariners dropped 2 of 3 games to the visiting Los Angeles Angels after the Guardians left town. Seattle fell 4-3 (as a +145 underdog) to L.A. and SP Shohei Ohtani in Wednesday's series finale. The Under 7.5 cashed by a hook, snapping a 3-0 Over run for the M's.