Sweet 16 odds, point spreads for men's NCAA tournament

With the first two rounds of the men's basketball NCAA tournament complete, we're down to the Sweet 16 for another year. Now, with a few days off before the next round, it's time to look at some point spreads, money-line odds and over/unders for the regional semifinals.

It's no surprise that the remaining No. 1 seeds, Alabama and Houston, are not only the national title favorites but also heavy chalk in their next matchup. The Crimson Tide is a 7½-point favorite over No. 5 seed San Diego State in the South Region, while the Cougars are -7 against No. 5 Miami in the Midwest. (VOTE: Which underdog is most likely to make the Final Four?)

But the biggest favorite in the Sweet 16 is actually South No. 6 seed Creighton, which drew No. 15 seed Princeton and is favored by 9½. But beware: Last season, No. 15 seed St. Peter's beat No. 3 Purdue outright as a 13-point underdog.

Only one lower seed is favored. That's Michigan State, which is 2-point chalk as the East No. 7 seed over No. 3 Kansas State. 

Here is a complete list of lines and over/unders from Caesars Sportsbook, official odds partner of Bet.NOLA.com:

Sweet 16 odds

(As of Tuesday morning; view updated lines here)

THURSDAY'S GAMES

East Region: No. 7 Michigan State (-2, ML -135) vs. No. 3 Kansas State (ML +115, o/u 137½), 5:30 p.m.

West Region: No. 4 UConn (-3½, ML -165) vs. No. 8 Arkansas (ML +140, o/u 140), 6:15 p.m.

East Region: No. 4 Tennessee (-5½, ML -240) vs. No. 9 Florida Atlantic (ML +195, o/u 130½), 8 p.m.

West Region: No. 2 UCLA (-2, ML -135) vs. No. 3 Gonzaga (ML +115, o/u 145½), 8:45 p.m.

FRIDAY'S GAMES

South Region: No. 1 Alabama (-7½, ML -355) vs. No. 5 San Diego State (ML +278, o/u 137), 5:30 p.m.

Midwest Region: No. 1 Houston (-7, ML -335) vs. No. 5 Miami (ML +260, o/u 138), 6:15 p.m.

South Region: No. 6 Creighton (-9½, ML 480) vs. No. 15 Princeton (ML +360, o/u 140), 8 p.m.

Midwest Region: No. 2 Texas (-4, ML -180) vs. No. 3 Xavier (ML +152, o/u 148½), 8:45 p.m.