Tennessee vs. Florida odds, prediction, spread: 2022 SEC on CBS college football picks by model on 51-43 run

No. 11 Tennessee Volunteers host the No. 20 Florida Gators on Saturday at 3:30 p.m. ET in Knoxville. The game is being broadcast live on CBS. Caesars Sportsbook lists the Volunteers as 10.5-point home favorites. Florida leads the all-time series by a 31-20 record. SportsLine's computer model simulates every FBS college football game 10,000 times and has returned a profit of more than $3,300 for $100 players on its top-rated collegeFootball picks against the spread.

SportsLine's computer model has revealed its picks and CFB predictions for Florida vs. Tennessee. Florida is 1-2 against the spread this season and Tennessee is 3-0 against a spread in 2022.

Tennessee and Florida are playing in the 2022 SEC on CBS college football game. The game is a 10-point favorite for Tennessee.

Florida is 16-1 against Tennessee in the last 17 meetings. Florida has scored at least 31 points in each of the past four games. The Gators are also out-gaining Tennessee by more than 100 yards per game. Anthony Richardson is a dual-threat quarterback with sky-high upside.

Tennessee is averaging 553.7 yards and 52.0 points per game this season. The team is also tied for the SEC lead with 12 rushing touchdowns. Quarterback Hendon Hooker has thrown 17 touchdowns and no interceptions in the last six games dating back to the end of the 2021 season, and he is completing 68% of his passes. On defense, Tennessee is yielding only 14.3 points and 83.4 yards per match.

SportsLine's model is leaning Under on the total and projects 60 combined points. It also says one side of the spread hits more than 50% of time.