Trail Blazers vs. Hornets odds, line: 2022 NBA picks, Nov. 9 predictions from proven computer model

Damian Lillard and Anfernee Simons are expected to play for Portland Trail Blazers against Charlotte Hornets. Tip-off is set for 7 p.m. ET from the Spectrum Center. Charlotte is 1-4 this season, while Portland is 7-3 overall and 4-1 on the road. The Trail Blazer's are favored by 3.5 points.

SportsLine's computer model has picked Charlotte Hornets vs. Portland Trail Blazers. The model is using its advanced computer simulations to pick the winner.

Hornets vs. Trail Blazers money line is Charlotte +140, Portland -165. Hornets vs Trail Blazers over/under is 219.5 points.

The Hornets lost 108-100 to the Washington Wizards on Monday. LaMelo Ball, Gordon Hayward and Cody Martin are injured. Charlotte has been one of the better defensive teams this season. Washington is the team with the most blocks per game.

Josh Hart's late jumper helped the Trail Blazers beat the Heat 110-107 on Monday. The top scorers for Portland were Simons (25 points) and Grant (23 points). The Trail Blazer's hold the third-highest three-point percentage in the NBA (39.5%). Charlotte held the Wizards to just 26.3% from distance on Sunday, but opponents have hit 36. 3% of their threes against the Hornets. Grant and Jusuf Nurkic are questionable for Wednesday's game.

The model simulates Trail Blazers vs. Hornets 10,000 times and it's leaning Over. It also generated a point-spread pick that's hitting in over 50% of simulations.