UFC 295 Betting Odds: Latest lines for Prochazka vs. Pereira & more

UFC 295, taking place at Madison Square Garden on November 11, is shaping up to be a blockbuster event, headlined by a light heavyweight title bout that pits Jiri Prochazka against Alex Pereira.

The highly-anticipated event is exclusive to ESPN+ PPV in the United States. Fans must, therefore order the event on ESPN+ to watch all of the action live on Saturday night

• Early Prelims: 6 p.m. ET
• Prelims: 8 p.m. ET
• Main Card: 10 p.m. ET

Here’s a detailed look at each of the main card fights, including the best odds for each fight.

• Jiri Prochazka: +100 (BetUS)
• Alex Pereira: -130 (BetUS)

Prochazka, after a shoulder injury hiatus, is returning with a 3-0 UFC record and a 13-fight win streak, facing Pereira who’s had an impressive year, including a win to claim the middleweight title.

This fight is a stylistic showdown; Prochazka’s unpredictable, fluid combat style contrasts Pereira’s structured, fundamental approach, both possessing knockout power​.

• Sergei Pavlovich: -110 (BetUS)
• Tom Aspinall: -120 (BetUS)

In the co-main event, the interim heavyweight title is up for grabs as Sergei Pavlovich faces Tom Aspinall. Pavlovich is riding a wave of first-round finishes, with an incredible reach that has served him well in his recent bouts.

Aspinall, known for his all-around talent, has sharp boxing and grappling, making a quick return after an injury with a win in July. They represent the top ascending talents in the heavyweight division, promising a battle that could define future title contentions​.

• Jessica Andrade: +165 (BetUS)
• Mackenzie Dern: -195 (BetUS)

The women’s strawweight bout features Jessica Andrade versus Mackenzie Dern, a fight critical for both fighters. Andrade, a former champion, is on a three-fight losing streak, looking to get back on track.

Dern comes off a win against Angela Hill, and though she has had mixed results in her recent fights, her grappling prowess remains her strongest asset. This bout could have significant implications for the 115-pound division​.

• Matt Frevola: +190 (BetUS)
• Benoit Saint-Denis: -230 (BetUS)

The lightweight bout between Matt Frevola and Benoit Saint Denis promises to be an electrifying opener for the main card.

Frevola, after a series of first-round stoppages, is on a surge, while Saint Denis, with a string of finishes since moving to lightweight, looks to cap off his year with another victory. Expect high-octane action from the get-go, with the potential for a spectacular finish​.

• Diego Lopes: -110 (BetUS)
• Pat Sabatini: -120 (BetUS)

Finally, featherweights Diego Lopes and Pat Sabatini square off in what promises to be a strategic ground battle. Lopes has shown dynamic aggression in his grappling, while Sabatini employs a more methodical approach.

Both fighters are on the cusp of breaking into the top 15, making this bout a potential stepping stone to higher rankings​​.

Here are the latest UFC 295 betting odds for every fight taking place this weekend.