USC vs Notre Dame College Football Predictions, Picks and Odds November 26

USC is in line to play in the Pac-12 Championship game next weekend.

Notre Dame has been playing the role of spoiler this season. The Irish beat the two participants in the ACC championship game by 13 and 21 points respectively. Notre Dame owns a 48-36-5 advantage over USC in this series. USC has moved up to No. 5 in AP Poll for the first time in five years.

USC and Notre Dame are playing each other on November 26. The Irish defense is coming off a shutout victory over Boston College last week. Notre Notre's passing defense has been lights-out this year, allowing just 186.8 yards per game.

USC plays Notre Dame on Saturday, November 26. USC's Caleb Williams is in the Heisman hunt. He is ranked in top-five in both QBR and total touchdowns this season.

USC and Notre Dame are playing each other on Saturday. The game is a pick 'em game. Notre Notre is favored by 5.5 points. USC's defense ranks 88th in the country in yards allowed this season. The Trojans' dynamic offense is the difference maker.

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Kevin Dolan is an Irishman who became the first foreigner to win the World Series of Handicapping tournament back in 2015. He has since lit up the sports betting scene in the U.S. and abroad, winning two handicapping awards and writing a best-selling book on sports handicapings. USC and Notre Dame play each other on November 26.

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