USC vs Stanford Odds, Preview & Prediction

USC is an 8-point favorite in its Pac-12 opener against in-state rival Stanford on Saturday (September 10th) at 7:30 pm ET on ABC. The Cardinal are 4-1 over their last five home games against the Trojans. USC is only 2-6 ATS in the last eight series meetings.

USC is -360 on the moneyline in the college football odds. They have 78.3% implied win probability.

USC is one game into the new season and has already won its first game. The team's two marquee transfers, Caleb Williams and Jordan Addison, scored two touchdowns each in the win over Rice. Austin Jones, a former Stanford tailback, also had a good game, rushing for 48 yards on four carries. USC's defense forced 24 turnovers last season. Stanford is the No. 10 team in America.

Stanford beat Colgate 41-10 in the season opener. The Cardinal's rushing production was up from last season. E.J. Smith got the win started with an 87-yard scamper 18 seconds into the game. He had 118 yards on 11 carries. Tanner McKee was 22-of-27 passing for 308 yards and a pair of touchdowns.