Wednesday NHL Odds, Picks, Prediction: Pittsburgh Penguins vs. Buffalo Sabres Betting Preview

Buffalo Sabres host Pittsburgh Penguins in Wednesday's NHL action. The Penguins are the favorites. Tony Sartori is backing Buffalo to win.

Pittsburgh Penguins are the favorites against Buffalo Sabres. Tony Sartori is backing Buffalo to win the game.

Pittsburgh Penguins are third in the Metropolitan Division and travel to Buffalo to play the Sabres. This is the third meeting between these teams, with them splitting the first two games.

Pittsburgh Penguins are playing their second game of a back-to-back set against Buffalo. The Penguins lost the first game against the Columbus Blue Jackets. Pittsburgh is 11-10-1 in its last 21 games. Buffalo is playing its third game in four days.

Buffalo Sabres are looking to upset the New York Islanders. The Sabres have won four of their last five games. They were big underdogs in all four games, but have fared well recently when priced as an underdog. Craig Anderson is the confirmed starting goaltender for Buffalo. He is 6-3 with an outstanding 0.923 save percentage at home this season.

Buffalo Sabres are playing their third game in four days. They are defending their home ice on national television. Anderson has been great between the pipes all season at the KeyBank Center. Buffalo is a +185 favorite.

Pittsburgh Penguins are playing Buffalo Sabres on Wednesday.