Week 13 College Football Picks Against the Spread

The final regular season week of college football brings with it a special vibe. Rivalry games dot the board and deliver a season's worth of gloating/deflecting to the participants. No. 2 Ohio State and No 3 Michigan play for a berth in the Big Ten title game and a sure spot in CFP Final Four. USC plays a rivalry game against No 15 Notre Dame fresh off a 45-42 victory over UCLA.

Ohio State is a 7.5-point favorite against Michigan. The game will be played at Ohio Stadium. Michigan won the last game 45-27. Ohio State hired a new defensive coordinator. The Buckeyes are 9-0 SU and 6-3 ATS at home against the Wolverines since 2000. 2020 game was canceled because of COVID issues in the Michigan program.

Notre Dame is a favorite to beat USC at home. The game is being played in a rivalry game. The Irish have not been an underdog since 2016. They have won the last four games in the series. USC is ranked behind LSU in CFP rankings. Notre Dame has won 7-2 SU and 5-4 ATS since 2012.

Washington State beat Washington 40-13 in Seattle last season. Washington is the pick here behind quarterback Michael Penix. The Cougars have won three in a row and four straight against the number. Huskies have beaten Oregon and Oregon State and the Cougar lost to both.