Week 5 NFL Odds and Best Bets: Picks for Perfect 10 Contest

SI Sportsbook offers a free sports betting contest every week of the NFL season. The Perfect 10 contest finds a slate filled with six of 10 home teams listed as favorites. San Francisco is a 6.5-point home favorite against Carolina.

SI Sportsbook offers a weekly "Perfect 10" contest. The weekly game requires bettors to make 10 selections against the spread for a chance at a share of a $10,000 prize. Every bettor who picks at least six games correctly will be awarded consolation prizes in the form of free bets.

Jacksonville is a touchdown-plus betting favorite against Houston in Week 5. Tom Brady is 4-0 SU and 3-1 ATS against Atlanta since joining Tampa Bay. The Falcons are the only perfect 4/0 ATCO team in the NFL this season. Buffalo is the biggest favorite (-14.5) this year against Pittsburgh.

Sports Illustrated's team picks their best bets for the NFL's Week 5. The Vikings are a touchdown better than the Bears. Jacksonville hasn't beaten Houston since Trevor Lawrence's senior year of high school. Tampa Bay easily covers the 7.5 and will win by two touchdowns. Bill Enright picks the Buccaneers to beat Atlanta. Matt De Lima picks Los Angeles Chargers to win against the Browns. Craig Ellenport picks Chargers against Browns, who are 2-2. Bill Ehalt picks Philadelphia to defeat Arizona. Sports Illustrated picks the Perfect 10 Contest. It's a contest to pick the best picks.