Yankees vs. White Sox odds, prediction, line: 2022 MLB picks, Sunday, May 22 best bets from proven model

The New York Yankees host the Chicago White Sox on Sunday Night Baseball at 7:08 p.m. ET. New England beat Chicago 7-5 on Saturday. Luis Severino (3-0, 3.63 ERA) gets the start for New Yorkers, while Michael Kopech (0-1, 1.54 ERA), takes the mound for Chicago. The Yankees are a money-line favorite, but Chicago is a +150 underdog. SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a profitable start to the 2022 season.

SportsLine's model has set its sights on White Sox vs. Yankees. The model is using its advanced predictions. SportsLine has a lot of MLB odds and trends for Yankees vs White Sells.

Yankees vs. White Sox is a Sunday game. The Yankees are 4-1 in their last 5 Sunday games. Chicago is 8-3 in its last 11 road games and the Yankees have won four of the last five.

Aaron Judge is a sensational hitter with top-notch power. Giancarlo Stanton has been red-hot to kick off this campaign. Stanton currently leads the team in batting average, RBIs, and hits.

Jose Abreu is a complete hitter with an explosive bat. Tim Anderson is an athlete with great instincts on the field. Anderson leads the team in batting average, on-base percentage, and hits.

Yankees vs. White Sox is Sunday, May 22.