49ers vs. Packers picks, prediction, player props: NFL odds

History will be made on Thursday when the Green Bay Packers and San Francisco 49ers kick off their contest in the NFC Divisional Round. Levi's Stadium plays host to the record-10th meeting between two franchises in the NFL Playoffs. It's a battle between the No. 1 and No. 7 seeds in the NFC, will the Packers tie up the postseason series or will the 49ers extend their advantage?

The historic contest is set to kick off at 7:15 p.m. CT from Santa Clara, California. Fox will carry the national broadcast with Kevin Burkhardt and Greg Olsen on the call. FanDuel Sportsbook is favoring the hosts by nearly 10 points with an over/under set at 50.5.

Let's take a closer look at the odds and highlight our favorite player prop plays in this NFC Divisional Round duel:

Green Bay Packers at San Francisco 49ers

Time/TV: Saturday, Jan. 20, at 7:15 p.m. (Fox)

Spread: 49ers -9.5

Over/Under: 50.5

Moneyline: 49ers -450, Packers +350

PLAYER PROP PICKS

Jordan Love NO interceptions (+118 at FanDuel Sportsbook)

Jordan Love has been phenomenal during his first year under center as the starting signal caller for the Green Bay Packers. He's been especially impressive over the last couple of months as he's gotten more comfortable under center and led the Packers to the playoffs. His display in Dallas was nothing short of superb during Super Wild Card Weekend, but now he will face his toughest test to date.

Love has played mistake-free football as of late with just one interception in the last two months. He's also thrown 21 touchdowns in the same time span, in case anybody needed context as to how impressive that feat is for someone with minimal experience as a starter.

Love faces a defense in the Divisional Round that was joint-first in the NFL with 22 interceptions forced this year. He has already gotten through two games with the Chicago Bears, the co-leaders with the 49ers, without turning the ball over. There's a plus sign next to Love's name to play turnover-free football again against San Francisco, so call me a sucker if you must, I'm taking it.

Christian McCaffrey OVER 89.5 rushing yards (-114 at FanDuel Sportsbook)

Christian McCaffrey has arguably been the best player in football this season. He's been so instrumental to San Francisco's success that he's going to finish inside the Top 5 — if not Top 3 — in NFL MVP voting. McCaffrey has a legitimate argument to win a quarterback award, and that's all you really need to know about his sensational showing this year.

The Stanford product has gone over the total for his rushing prop five times in the last six games. Four of those games saw him go over 100 yards, a feat he achieved seven times this season. Green Bay has the 28th-rated rush defense in the league. The Packers gave up an average of 128 yards per game throughout the regular season, 141.4 yards per game away from Lambeau Field. It's hard to imagine this poor rush defense stopping the best back the NFL has to offer.

Luke Musgrave OVER 18.5 receiving yards (-122 at FanDuel Sportsbook)

Trying to predict the Packers' passing patterns in any given game is a crapshoot. You'd be better off placing the names of receivers on a dart board and deciding who to bet on that way. There's a lot of inconsistency there due to the inexperience across the board in Green Bay's passing game. Nevertheless, I've found what I believe to be a safe play for the contest in San Francisco.

Musgrave's enjoyed a solid — not spectacular — rookie season as one of the Packers' young tight ends. He's just recently returned from an injury and he marked his return bringing in every target for 52 yards and a touchdown against the Cowboys. His prop is set at a measly 18.5 receiving yards, a mark he's surpassed in 75% of the games in which he's played. San Francisco has also surrendered the seventh-most receiving yards to opposing tight ends this year.