Cowboys vs. 49ers Player Prop Bets for Sunday Night Football: Dak Prescott, CeeDee Lamb, Christian McCaffrey, Brandon Aiyuk, and Others

The Dallas Cowboys vs. San Francisco 49ers on Sunday Night Football features two elite NFC teams with an abundance of skill-position talent. But each set of playmakers will be going against, by far, the best defense they have faced all season, as the Cowboys and 49ers each have top-five units through four weeks of the NFL season.

Will Christian McCaffrey continue his hot streak against this Cowboys defense? Will Dak Prescott have his breakout game of the season on the big stage? PFN’s betting team gives their favorite Cowboys vs. 49ers player prop bets for Sunday Night Football.

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Top Dallas Cowboys vs. San Francisco 49ers Player Prop Bets To Target

All odds are from DraftKings Sportsbook unless noted otherwise.

Dak Prescott Player Props

• Passing Yards: 241.5 (Over -115/Under -115)
• Pass Touchdowns: 1.5 (Over +114/Under -145)
• Pass Completions: 23.5 (Over +100/Under -130)
• Pass Attempts: 34.5 (Over -110/Under -120)
• Interceptions: 0.5 (Over -135/Under +105)

Blewis: Dak Prescott has really only been tested in one game this season, as they have won by at least 20 points in three out of four games. As a result, the Cowboys rank fourth-last in pass rate so far this season. That should change tonight, however, as this game shouldn’t be a blowout one way or the other.

The biggest difference in Prescott’s game so far this season without Kellen Moore as his OC is that aDOT has dropped considerably, from 8.6 to 6.2, which is the lowest in the league of starting QBs. As a result of his shorter aDOT, his completion percentage has increased by 5%.

With all of this in mind, let’s grab the over on his pass completions, which is still 22.5 at FanDuel.

Player Prop Bet: Dak Prescott over 22.5 completions (-122 at FanDuel)

Tony Pollard Player Props

• Rushing Yards: 56.5 (Over -125/Under -105)
• Rush Attempts: 15.5 (Over +100/Under -130)
• Receiving Yards: 21.5 (Over -115/Under -115)
• Receptions: 3.5 (Over +124/Under -160)
• Anytime Touchdown Scorer: -115
• First Touchdown Scorer: +600

Blewis: As the new lead back in Dallas, Tony Pollard has 53 more carries than the next closest running back this season, and he’s been heavily featured around the goal line as well. Out of all running backs, he’s currently in a three-way tie for the 3rd-most carries inside the 5-yard line this season. Yet, he only has two TDs in four games. Let’s take a chance on him getting into the end zone tonight.

Player Prop Bet: Tony Pollard anytime touchdown (-115 at DraftKings)

CeeDee Lamb Player Props

• Receiving Yards: 68.5 (Over -115/Under -115)
• Receptions: 5.5 (Over -140/Under +110)
• Longest Reception: 22.5 (Over -120/Under -110)
• Anytime Touchdown Scorer: +170
• First Touchdown Scorer: +1100

Blewis: CeeDee Lamb has gone under tonight’s receiving yards prop line of 68.5 in two consecutive games. His targets have been relatively low so far this season, which is largely due to the game script, considering three-quarters of the Cowboys games this season have been blowouts.

Tonight’s game should be much closer. To find some correlation with my over on Prescott’s completions tonight, let’s go with Lamb’s over for receptions.

As good as the 49ers’ defense is, they have allowed Marquise Brown to record seven receptions and Puka Nacua to have 15 against them. They might be an elite unit, but good wide receivers are more than capable of getting open against their secondary.

Player Prop Bet: CeeDee Lamb over 5.5 receptions (-140 at DraftKings)

Brandin Cooks Player Props

• Receiving Yards: 38.5 (Over -120/Under -110)
• Receptions: 3.5 (Over -120/Under -110)
• Longest Reception: 22.5 (Over -120/Under -110)
• Anytime Touchdown Scorer: +310
• First Touchdown Scorer: +2000

Katz: It’s hard to get a read on the Cowboys passing game. They have yet to play a normal game. Three of their first four contests were noncompetitive blowouts with multiple defensive scores. The other one was a loss to the Cardinals, where the game wasn’t really competitive in the other direction.

With that said, it sure looks like Brandin Cooks is a shell of his former self. He’s averaging just five targets a game and has yet to exceed 27 receiving yards. Yet, his line is set at 38.5.

Perhaps it’s this high because the expectation is this game will be competitive, and the Cowboys will have to throw to keep pace with the 49ers offense. But there’s definitely a world where these two elite defenses dominate, keeping the game low-scoring. Either way, this line looks too high.

Player Prop Bet: Brandin Cooks under 38.5 receiving yards (-110 at DraftKings)

Jake Ferguson Player Props

• Receiving Yards: 30.5 (Over -110/Under -120)
• Receptions: 3.5 (Over -130/Under +100)
• Longest Reception: 14.5 (Over -105/Under -125)
• Anytime Touchdown Scorer: +310
• First Touchdown Scorer: +1900

Soppe: San Francisco owns the seventh lowest blitz rate (eighth highest in hurry rate) through four weeks, a defensive game plan that suggests that chunk plays through the air could be hard to come by, with the short pass game instead being their only bet.

2023 aDOT:

• Michael Gallup: 8.9
• CeeDee Lamb: 7.9
• Brandin Cooks: 7.4
• Jake Ferguson: 4.4

We can agree that Dak’s best days as a runner are behind him (one game since Halloween with 25 rush yards), right? The 49ers have played one stuck-to-the-pocket QB this season (Week 2 at Matthew Stafford). That week, Stafford’s aDOT was 28.3% lower than his other three games this season, something I think we see happen to Prescott.

Player Prop Bet: Jake Ferguson over 28.5 receiving yards (-114 at FanDuel, fine with going up to 50+ receiving yards if you’re chasing a plus money option!)

Brock Purdy Player Props

• Passing Yards: 245.5 (Over -115/Under -115)
• Pass Touchdowns: 1.5 (Over -105/Under -125)
• Pass Completions: 20.5 (Over -130/Under +100)
• Pass Attempts: 30.5 (Over -130/Under +100)
• Interceptions: 0.5 (Over +124/Under -160)

Blewis: Brock Purdy has faced the 14th, 21st, 28th, and 29th best defenses by EPA/play so far this season. Tonight, he faces by far his biggest test yet, as the Cowboys’ defense has been the second-best this season behind the Browns.

Purdy has taken pretty good care of the football, having thrown just four interception-worthy passes so far this season, but at +134 odds at FanDuel, it’s an appealing number when you consider he’s going to throw one eventually, and this Cowboys defense is excellent at creating takeaways.

Player Prop Bet: Lean Brock Purdy to throw an interception (+134 at FanDuel)

Christian McCaffrey Player Props

• Rushing Yards: 78.5 (Over -115/Under -115)
• Rush Attempts: 17.5 (Over -140/Under +110)
• Receiving Yards: 32.5 (Over -115/Under -115)
• Receptions: 4.5 (Over +114/Under -145)
• Anytime Touchdown Scorer: -210
• First Touchdown Scorer: +330

Blewis: This Cowboys defense has been the second-best unit by EPA/play this season behind the Browns, but if there’s one weakness for them, it’s stopping the run, ranking 27th in success rate. Their run defense hasn’t really been tested this season, as three of their four games have been blowout wins. But in their loss to the Arizona Cardinals, they allowed them to run for 222 yards and averaged 7.4 yards per carry.

Tonight, they’ll be facing the best running back in football in Christian McCaffrey, who is on an absolute heater. Given the mismatch of the 49ers’ offensive line vs. the Cowboys pass rush, I’m expecting a more conservative game plan from Kyle Shanahan, so I’ll be taking McCaffrey’s rushing yards over.

Player Prop Bet: Christian McCaffrey over 78.5 rushing yards (-115 at DraftKings)

Deebo Samuel Player Props

• Receiving Yards: 47.5 (Over -115/Under -115)
• Receptions: 4.5 (Over +110/Under -140)
• Longest Reception: 20.5 (Over -115/Under -115)
• Anytime Touchdown Scorer: +145
• First Touchdown Scorer: +850

Blewis: In a somewhat surprising development, Deebo Samuel is no longer the most targeted 49ers’ wide receiver in the passing game, as Brandon Aiyuk’s target rate is nearly 5% higher so far this season.

In the one game Aiyuk missed, Samuel had 12 targets, catching six of them for 129 yards. In the two games before that, he had a combined 16 targets for 118 yards.

Samuel’s status for tonight was possibly in doubt earlier this week as he was a limited participant with a rib injury. Even though it’s confirmed he will be playing tonight, there’s a chance he’s playing through an injury which could limit his impact in the passing game as well here.

Player Prop Bet: Lean Deebo Samuel under 4.5 receptions (-140 at DraftKings)

Brandon Aiyuk Player Props

• Receiving Yards: 57.5 (Over -135/Under +105)
• Receptions: 4.5 (Over +114/Under -145)
• Longest Reception: 23.5 (Over -110/Under -120)
• Anytime Touchdown Scorer: +150
• First Touchdown Scorer: +850

As I mentioned above, Brandon Aiyuk is now the number-one target in the 49ers’ passing offense, and he has been extremely productive so far this season. In three games, he has 320 yards receiving and two TDs.

The Cowboys lost their best cornerback, Trevon Diggs, a couple of weeks ago to a season-ending injury, but they haven’t really been tested against a legitimate No. 1 wide receiver since. Aiyuk has been one the best WRs in the NFL this season, averaging the sixth-most receiving yards per game. Yet, his line is only 57.5 tonight, which seems like an easy over.

Player Prop Bet: Brandon Aiyuk over 57.5 receiving yards (-135 at DraftKings)

Picks and Predictions for Every Game

Looking to get more advice for this week’s action? We’ve got picks and predictions for every matchup in Week 5. Use the table below to find the matchup you’re looking for.