San Diego Padres vs. San Francisco Giants Odds and Picks

San Diego Padres and San Francisco Giants are playing each other on Monday. San Diego is looking to put the finishing touches on a strong Wild Card campaign.

San Diego Padres and San Francisco Giants are playing a best-of-five series starting on Monday. San Diego has a chance of locking up the No. 2 Wild Card spot this week. The Giants would love to sweep the Padres to close out an otherwise disappointing 2022 campaign.

The first pitch is scheduled for 9:40 PM EST on October 3rd, 2022, at Petco Park in San Diego, CA.

The San Diego Padres are the home favorites against the San Francisco Giants on Monday. The Padres have a league-worst 27-50 record against run lines at their home field.

The Giants have been mediocre against the run line in 2022 but do own a solid 41-37 against-the-run-line record when playing on the road. The Giants are playing the Padres on Monday.

Joe Musgrove will start for the Padres against John Brebbia for San Francisco. Brebba has had a good season, but he probably won't go more than two innings.

Joe Musgrove didn't allow a run but he also gave up four free passes and lasted just five innings. Musgrave has only pitched six innings or more in one of his past five starts. San Diego is hoping to lock up the second spot in the NL Wild Card race.

Joe Musgrove will work at least five innings for San Diego and the bullpen will wrap things up for the Giants. San Francisco has struggled in 2022, while SanDiego has dealt with inconsistency.

San Diego Padres are playing San Francisco Giants in a Monday night game. The Padres have already clinched a postseason spot, but they want to ensure they lock up the second Wild Card spot. San Diego is currently one game ahead of Philadelphia in the Wildcard race.