2022 MLB playoffs: Mariners vs. Blue Jays odds, line, Wild Card Series Game 1 picks, predictions by top model

The 2022 MLB playoffs begin on Friday with the Seattle Mariners and Toronto Blue Jays playing a three-game Wild Card Series. First pitch is at 4:07 p.m. ET in Toronto. The Mariners broke the longest playoff drought in MLB with 90 wins this season, while the Blue Jay produced 92 victories this year. Caesars Sportsbook lists Toronto as a -135 favorite on the money line. SportsLine's advanced computer simulation model simulates every MLB game 10,000 times. It returned almost $700 for $100 players last week.

SportsLine's advanced model has set its sights on Mariners vs. Blue Jays and has made its picks and MLB playoff predictions. SportsLine has provided several MLB odds and betting lines for Mariners and Blue Jay.

Mariners vs. Blue Jays money line is Blue Jay's -135, Mariners +115. Over/under is 7 runs. Mariners are 44-37 in road games, Bluejay's 47-34 at home.

The Seattle Mariners are going to play the Blue Jays in the 2022 MLB playoffs. Luis Castillo is a two-time All-Star and has a 2.99 ERA and a 1.08 WHIP this season. Seattle's offense ranks No. 2 in American League with 596 walks and 197 home runs.

Toronto is a potent offensive team. Seattle is not. The Blue Jays were No. 3 in the American League in home runs this season. They were also No 2 in runs and doubles. In contrast, Seattle was No 14 in hits, No 12 in doubles and No 13 in strikeout avoidance.

SportsLine's model is leaning Over on the run total. One side of the money line has all the value.