2023 ACC Championship Game odds, line: Louisville vs. Florida State picks, prediction by expert who's 73-28

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2023 ACC Championship Game odds, line: Louisville vs. Florida State picks, prediction by expert who's 73-28

No. 4 Florida State will try to stay in the College Football Playoff picture when it hosts No. 14 Louisville on Saturday night. The Seminoles (12-0) completed a perfect regular season with a 24-15 win at Florida last week, but they are playing without starting quarterback Jordan Travis (leg) and potentially without backup Tate Rodemaker, who will be a game-day decision (head). Louisville had its four-game winning streak snapped in a 38-31 loss to Kentucky in last week's rivalry game. The Cardinals and Seminoles did not meet during the regular season. 

Kickoff is set for 8 p.m. ET at Bank of America Stadium. The Seminoles are 1-point favorites in the latest Florida State vs. Louisville odds from SportsLine consensus, while the over/under is 46.5. Before locking in any ACC Championship picks, be sure to check out the college football predictions and betting advice from SportsLine football expert Jimmie Kaylor

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has been red-hot all season, going 73-28-2 overall on his college football best bets for SportsLine this season so far. He is up over 46.05 units, returning a profit of $4,605 for $100 bettors. Anyone who has followed his picks this season is way up.

Now, he has set his sights on FSU vs. Louisville and just locked in his picks and CFB predictions. You can head to SportsLine now to see Kaylor's picks. Here are several college football odds and betting lines for Louisville vs. FSU:

  • Louisville vs. Florida State spread: Florida State -1
  • Louisville vs. Florida State over/under: 46.5
  • Louisville vs. Florida State money line: Florida State -121, Louisville +101
  • FSU: The Seminoles have won 11 consecutive ACC games.  
  • LVILLE: The Cardinals have won 11 of their last 13 games. 
  • Louisville vs. Florida State picks: See picks at SportsLine
  • Louisville vs. Florida State live stream: fubo (try for free)

Why Florida State can cover

Florida State has won 11 straight games against ACC teams dating back to last season, as the Seminoles have been the best team in the conference this season. They overcame Travis' injury last week, beating Florida by nine points with Rodemaker under center, and FSU has a strong rushing attack to rely on whether it is Rodemaker or third-stringer Brock Glenn starting at QB.

Junior running back Trey Benson rushed for 95 yards and three touchdowns against the Gators, averaging 5.0 yards per carry. He has cracked the 80-yard mark in three of his last four games, scoring seven total touchdowns during that stretch. Louisville gave up 159 rushing yards and three touchdowns to Miami's running backs two weeks ago, putting the Cardinals in a difficult position on Saturday night. See which team to pick at SportsLine

Why Louisville can cover

Louisville has an elite defense of its own, allowing just 20 points per game this season. The Cardinals can win their first conference title since the 2012 Big East title, putting them in line for an Orange Bowl berth. First-year head coach Jeff Brohm has been outstanding, leading his team to wins over Notre Dame, Duke and Miami

Quarterback Jack Plummer has racked up 2,952 passing yards and 21 touchdowns, giving Louisville more firepower at the quarterback position. Running back Jawhar Jordan is the ACC's second-leading rusher in yardage (1,076) and has scored 13 touchdowns. The Cardinals have covered the spread in five of their last seven games against Florida State. See which team to back at SportsLine.

How to make ACC Championship picks

Kaylor has analyzed this matchup from every angle and he's leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.