Baltimore Orioles vs. Boston Red Sox Odds, Pick, Prediction 9/26/22

The Baltimore Orioles and Boston Red Sox are playing a divisional duel on Monday, September 26. The Red Sides are -135 moneyline favorites on MyBookie Sportsbook. This is the first of a four-game series at Fenway Park.

Orioles lost the home series against the Houston Astros 6-3. Baltimore is four wins behind the Seattle Mariners in the wildcard race. Rougned Odor was a bright spot for Baltimore. Jordan Lyles is getting his 31st start of the year when he takes on the Red Sox on Monday.

The Boston Red Sox are on a losing streak and are in danger of being swept by the New York Yankees. The Red SO have lost four consecutive games and 11 of the last 16. They lost 7-5 to the Yankees on Sunday night. Connor Seabold will start for the 5th time this year against the Baltimore Orioles on Monday.

Baltimore Orioles are 4-0 in the last four games vs. a right-handed starter and 5-2 in last seven road games. Boston Red Sox are 14-6 in games 1 of a series during the past 20.

Baltimore Orioles are 4-0 in the last four games vs. a right-handed starter and 5-2 in last seven road games. Boston Red Sox are 14-6 in their last 20 games during a series.

Boston Red Sox are 0-4 in the last four games and 5-5 in last five games against a right-handed starter. Boston Red SOf the Orioles are 17-41 in 58 games vs. American League East rivals.

Baltimore Orioles are 0-4 in the last four games overall and 5-5 in last five games against a right-handed starter. Boston Red Sox are 17-41 in 58 games vs. American League East rivals.

Connor Seabold has allowed 4+ runs in three of his four starts this season. Jordan Lyles had the second complete game of 11-year career and signed a new one- year $7 million contract with the Orioles. The Orioles are 4-0 in Lyle's last four games with four days of rest.

Baltimore Orioles and Boston Red Sox are playing on 9/26/22. The total is 9.0-10.5 runs. Lyles has an 8.00 ERA in four starts against Boston this season. Over is 3-0 in Lyle's last four games against a team with a losing record.