BYU vs Oregon Odds, Picks & Predictions

No. 12 BYU Cougars and No. 25 Oregon Ducks meet in Eugene on Saturday afternoon. BYU is coming off a 26-20 double-overtime win at home against the then-No 9 Baylor Bears. Oregon rebounded from a 49-3 loss to No 1 Georgia in Week 1 by beating Eastern Washington 70-14.

BYU beat Baylor 50-21 in overtime last Saturday. Puka Nacua and Gunner Romney are questionable for this week's game. Baylor held BYU to 83 rushing yards on 33 carries. The defense should be able to stop Oregon's new quarterback Bo Nix. Georgia's offense is better than Oregon. Georgia beat Oregon in the Chick-fil-A Kickoff Game. Both teams will play a low-scoring game early. They will try to establish something from the run game in this game, but it will be hard. It will also be difficult for them to figure each other out in second half.

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BYU is 2-0 against the spread this season in Kalani Sitake's seventh year as head coach. The Cougars are 5-13 SU in their last 18 games as a road underdog. Oregon has been less than stellar to start Dan Lanning's tenure. Since 1995, the Ducks are 13-2 SU and 11-4 ATS when favored at home by less that four points.

BYU and Oregon are playing each other on Saturday. The total opened at 57 at most sportsbooks and shifted a point to 58 at PointsBet and Caesars. Oregon's offense struggled against Georgia's top-ranked defense. BYU's defense let Baylor go 9 of 18 on third down, while the Cougars' offense converted on just 3 of 14 third-down tries.

BYU vs Oregon is a college football game.

BYU is 1-4 ATS in its last five road games.