Cincinnati Bengals vs Buffalo Bills Predictions, Picks & MNF Best Bets

Cincinnati Bengals host Buffalo Bills on Monday Night Football. The Bengals are currently the No. 1 seed in the AFC, while the Bills are the current No 1 overall seed thanks to a win over the Chiefs.

Bills are favored by a single point against Bengals. Over/Under is 49.5 points. Ohioans will be able to wager on Ohio betting apps for this one.

Bills have won six straight games. Bengals have lost just three times, all by a FG or less. Cincy has won seven straight and hasn't lost at home since Week 1.

The 49.5 points is the second-highest total of the week. The Under is 7-1 in Bills road games and 7 of 7 in games against teams with a winning record.

Buffalo is just -115 on the moneyline, while host Cincinnati is -105.

Josh Allen has gained over 48 rushing yards seven times and been held under 48 yards eight times. The Bengals have allowed a league-low 45 QB runs and are giving up just 12.9 yards per game.

Josh Allen has over 240 pass yards per game this season. He has eight games above this total on the year. In six games against teams currently in a playoff position, Allen averaged 315.5 ypg.