College Basketball Best Bets Friday: Matchups, Odds, Picks, and Predictions

It's the first weekend of the college basketball season. There's a lot of action on Friday. DraftKings Sportsbook and FanDuel Sportsbooks offer odds and best bets for Friday's college hoops.

Gonzaga is playing Michigan State on Friday. Villanova is taking on Temple. Clemson is facing South Carolina. Bryant is going to play Dartmouth. Longwood is also playing George Mason. Mississippi State is being played against Akron. USC Upstate is up against Duke.

Gonzaga is playing Michigan State. Villanova is taking on Temple. Clemson is facing South Carolina. Bryant is going to play Dartmouth. Longwood is against George Mason. Mississippi State is vs. Akron. USC Upstate is up against Duke.

Bryant is playing Dartmouth. Penn is covering against Missouri. Longwood-George Mason is under 133.5 points. Mississippi State is an upset against Akron.

Bryant is playing Dartmouth. Penn is taking on Missouri. Longwood-George Mason is under 133.5 points. Mississippi State is going to play Akron.

Bryant is coming off one of the biggest blowouts in Division I history after defeating Thomas College 147-39. The Bulldogs are expected to compete in the America East. They play Dartmouth in New Hampshire on Friday. Dartmouth is expected by many to finish second from the bottom in Ivy League. Bryant is favored by six points.

Penn lost its opening game to Iona. Missouri beat Southern Indiana, but the team is still finding its footing under a new coach Dennis Gates. Penn is preseason favorite to win the Ivy League. Missouri won only three games by more than this margin last season.

Both Longwood and George Mason lost their season-openergies to SEC teams. Longwoods lost to Alabama 75-54, while George Minsites lost against Auburn 70-52. Both teams are ranked in the low-to-mid 70s in offensive efficiency.

Akron beat South Dakota State 81-80 in the season opener. Mississippi State was 3-3 in neutral-site games last season. The Bulldogs take on Akron in Philadelphia on Friday. Akron has the third-highest KenPom ranking among MAC schools at No. 111.

Duke is favored by 27.5 points against USC Upstate. The Blue Devils have the No. 3 offensive efficiency in the country according to KenPom. USC is ranked No 112 in adjusted tempo and No 327 in defensive efficiency.

College basketball odds and best bets from 11/11/20222 at 2 p.m. ET.