College Football Odds, Picks and Predictions For Week 2

Virginia is listed as a 4.5-point underdog vs. Illinois in the College Football season's second game. Andrew Caley's Triple Option highlights the Cavaliers as one of three teams to zero in on in Week 2 of the season. Air Force is set to trample the Buffaloes. Mike Leach's Air Raid offense will cool off Arizona in Arizona.

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Air Force beat Northern Iowa 48-17. Colorado Buffaloes lost to TCU 38-13 last week. Air Force will use its efficient yet still explosive rushing attack to take advantage of the Colorado defense. The Falcons will cover the spread.   The team will win the game. They will play in-state rivals Colorado and Air force. It will be a rivalry game between the two teams.

Virginia beat Richmond 35-17 last week. Illinois lost to Indiana last time. The Illini were favored against Wyoming. Virginia is a high-octane offense led by one of the best quarterbacks in college football. Virginia and Illinois are going to play each other. They are both +110.5 at the betting window. It's possible that the wrong team might be favored here. If the Cavaliers' defense can force the Illins into a couple of turnovers, they might win the game outright.

Arizona beat San Diego State 38-20 in the season opener. Mississippi State beat Memphis 49-23 last week. The Bulldogs are a strong team with an air raid offense. Arizona's secondary is not very good. Mississippi will cover the spread. It's a good bet. They will win. This is the second game of the week for the Bulldogs. Their last game was a win over Memphis. SanDiego State is a bad team.

Michigan is a 50-point favorite against Hawaii. It's the seventh time since 2005 that an FBS team has been at least 50 points ahead of another FBC team.

Iowa State and Iowa are playing a game with a total of 39.5. Iowa's offense is a disaster. The game would have gone over 39 in four of the last six years.

Wake Forest quarterback Sam Hartman has been out since August 10 with a blood clot issue. Hartmann led Wake Forest to an ACC Atlantic title in 2021.