College football picks, predictions against the spread for Week 11 top 25 games

Summarized by: Live Sports Direct
 

No. 4 TCU is a seven-point underdog at No. 18 Texas in the Big 12. No 24 Washington meets No 6 Oregon in a Pac-12 rivalry at 7 p.m.

No. 10 Alabama takes on No. 12 Ole Miss at 3:30 p.m. No 22 UCF travels to No 16 Tulane in an American Athletic Conference game. There are 21 games involving AP Top 25 teams in Week 11.

No. 8 USC is favored by 34 points against Colorado. The Trojans should cover the spread. USC won the last two weeks.

The Hoosiers have lost six games in a row. Ohio State is 0-3 ATS when favored by 35 points or more this season. Tennessee is favored to beat Missouri 45-21. LSU is a short favorite against Arkansas. The Tigers are 4-0 AET as an underdog this year. Illinois is the better play against the Illini. The Midshipmen are a double-digit underdog. They are coming off Marcus Freeman's first victory as head coach. He won against Clemson. UConn is 8-2 ATC and is within one game of a bowl berth in his first season under Jim Mora Jr.

The Terps have three Big Ten losses by an average of 7.3 points per game. The Nittany Lions won at Beaver Stadium in their last visit in 2020.

Georgia is the favorite to beat Mississippi State 37-18. NC State is going to win 38-16. Oregon is 7-1 ATS since the loss to Georgia. Washington is favored to cover against Baylor. Texas is a favorite against TCU. Wake Forest is losing back-to-back games. The Tar Heels have the best offense in the ACC. Washington will beat Oregon 41-31 but not cover the spread. Baylor has won the last four games in a row. TCU is 6-2 in this series in CFP era. It's a double-take line considering Wake has lost back to back games and the Tarheels are the top-scoring team in ACC at 40.6 points per game.


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