College football picks, predictions against the spread for Week 12 top 25 games

Summarized by: Live Sports Direct
 

No. 7 USC takes on No. 16 UCLA at the Rose Bowl at 7:30 p.m. ET on ABC. The game is a chance for Heisman Trophy contender Caleb Williams to command the spotlight. There is also a Pac-12 championship game rematch between No 10 Utah and No 12 Oregon.

No. 21 Tulane is playing at SMU on Thursday at 7:30 p.m. (ESPN). The Mustangs have won the last seven games in the series. SMu is the top scorer in AAC at 40.3 points per game.

Navy and UCF are playing on Saturday. Florida State is rolling. Illinois hasn't won at the Big House since 2008. TCU is playing at Baylor. Kansas State plays at West Virginia. Oregon State takes on Arizona State.   The picks are for the Week 12 top 25 games. The games are on ESPN. They are: -7.5 at Oregon and -13. 5 at Arizona. It's a game between two teams that haven't met in the last two seasons.

Oregon State is 2-2 on the road and hasn't won at Arizona State since 2009. Boston College is playing at No. 18 Notre Dame. The game starts at 2:30 p.m. ET.

Notre Dame has won eight straight games in the series. Boston College is 3-3 ATS as a double-digit underdog. Georgia is coming off a loss to Vanderbilt. Ohio State is going to beat Michigan. Rutgers has failed to score more than 10 points in last eight games. Penn State has covered in four straight Big Ten games and is playing for 10th win. Cincinnati is 5-1 S/U in their last six games, including a 52-0 win over Temple. Clemson is chasing Miami's all-time home winning streak. The Tigers will become the 10 team to win 40 straight home games if they beat Miami.


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