Colts vs. Cowboys odds, spread, line: Sunday Night Football picks, predictions by NFL model on 155-110 run

Dallas Cowboys take on the Indianapolis Colts on Sunday Night Football. The Cowboys are coming off back-to-back impressive performances. Indianapolis has lost five of six games and is three games behind in the race for the last Wild Card spot. Dallas is a 10.5-point favorite. Over/under for total points scored is 44. 5. NFL model simulates every game 10,000 times and has made over $7,500 on top-rated NFL picks since its inception.

Colts vs. Cowboys is a Sunday Night Football game. The money line is Colts +430, Cowboys -600. Colts are 5-0 against the spread in their last five road games against teams with a winning home record. Dallas is 7-1 ATS in its last seven December games. SportsLine's advanced NFL model is on a 155-110 run.

Colts vs. Cowboys money line is Colts +430, Cowboys -600. Colts are 5-0 against the spread in their last five road games against teams with a winning home record. Dallas is 7-1 ATS in last seven games in December.

CeeDee Lamb had six catches for 106 yards last week in the win over the New York Giants. Micah Parsons had his ninth career two-plus sack game last weekend. He is the third player since 1982 with 12 or more sacks in each of his first two seasons. The model has a 155-110 run on Sunday Night Football picks.

Matt Ryan has completed 269 of 391 attempts for 2,642 yards and 11 touchdowns with 10 interceptions for a rating of 86.3. Ryan's best game this season came in a 34-27 win over Jacksonville on Oct. 16. Michael Pittman Jr. leads the receiving corps with a team-high 74 receptions for 739 yards (10.0 average) and two touchdowns.

SportsLine's model is leaning Over the point total and projecting 46 combined points. It has also generated an against-the-spread pick that hits in over 50% of simulations.