Florida State Seminoles vs. Louisville Cardinals: Odds, Line, Picks, and Predictions September 16, 2022

The Florida State Seminoles kick off their ACC play with this Friday night (September 16) game against the Louisville Cardinals. Florida state remain undefeated after upsetting LSU in their last game. Louisville lost their first game of the year to Syracuse on September 3 but came back stronger the following week against UCF.

LSU goes on a 99-yard drive and score with 0:00 on the clock. XP to tie the game is blocked.

Florida State Seminoles play Louisville Cardinals on September 16, 2022.

Florida State Seminoles vs. Louisville Cardinals is scheduled for September 16, 2022.

Louisville Cardinals haven't scored more than 20 this year. Florida State Seminoles haven’t scored 30+ every week. The over/under in this game is far too high.

Fan Duel offers a bet on Florida State Seminoles vs. Louisville Cardinals on September 16, 2022. The bet is on the under 56.5 (-105) bettors.

Florida State Seminoles vs. Louisville Cardinals is scheduled for September 16, 2022. First quarter is over 12 points.

Louisville's defense is terrible against the run. Florida State has not had the best running game this season. If they can break it out, they should easily win this game.