Florida State vs Louisville Week 3 Football Predictions and Best Bets

Florida State Seminoles and Louisville Cardinals will meet in Week 3 of the College Football season. The Seminole's are 2-0 and the Cardinals are 1-1. Last week, Florida State held on for a road win at LSU. Louisville won at UCF last week.

Florida State Seminoles (2-0) vs. Louisville Cardinals (1-1) is on Friday, September 16, 2022 at 7:30 p.m. Eastern Time. The game will be broadcast on ESPN.

Louisville and Florida State are playing each other in the ACC. The Seminoles hold the series edge 16-6. Louisville is on a 2-game winning streak against the Noles. They have played every year since 2014. In 2020, Louisville won 48-16 at home. The teams have scored 52 points or more in 5 games between them.

Louisville beats Florida State 38-35 in the Week 3 football game.

Florida State vs. Louisville is a game with over 57 points.