Florida State vs. Clemson odds & prediction for CFB Week 4: Tigers a home dog for first time since 2016

The No. 4 Florida State Seminoles have been one of college football's feel-good stories early in the 2023 season. FSU faces a stern test in Saturday's ACC showdown at Clemson in one of the biggest games on a loaded CFB Week 4 slate.

Take a quick peek to peruse and claim top sportsbook betting bonuses before we examine Florida State vs. Clemson odds, props & predictions.

Florida State vs. Clemson betting lines: point spread, moneyline & total

Here are Florida State vs. Clemson odds on top-rated sports betting apps:

 FSU vs. Clemson betting trends 

• Florida State is 2-1 against the spread (ATS) this season
• The Seminoles are 3-0 to the Over this year
• Clemson is 1-2 ATS this season
• The Tigers are 2-1 to the Over this year
• Clemson defeated FSU 34-28 last year and covered as a -4.5 favorite 

Florida State vs. Clemson analysis, prediction

Florida State is coming off a surprisingly narrow 31-29 win at Boston College in which the Seminoles were favored by as many as 24.5 points. FSU QB Jordan Travis was solid if not spectacular against BC with 212 passing yards and 2 TDs through the air. He left the game with an apparent shoulder injury but will reportedly be a full-go at Clemson.

Can Florida State round back into the form that carried them to a dominant 45-24 win over LSU in its season opener? Travis went off for 300+ yards and four TDs in that game and outperformed LSU stud QB Jayden Daniels.

Clemson brings a top-10 defense into this contest, allowing 3.85 yards per play and 246.7 yards per game. Those numbers are skewed a bit with games against lesser foes Charleston Southern and Florida Atlantic. The Tigers suffered a surprising 28-7 loss to Duke in their season opener. Clemson entered the game as a double-digit favorite against the Blue Devils.

Clemson finds itself in unfamiliar territory as a result of that loss. The Tigers are on the outside looking in at the AP's top-25 teams in the nation. Clemson is also a home underdog at Death Valley for the first time since 2016 when Louisville and QB Lamar Jackson came to town.

Florida State is a short favorite, though, with the line hovering between -1.5 to -2.5 across the industry. That's notable considering Clemson has won its last seven games against Florida State including four at home.

Will Shipley is Clemson's lead RB with 225 yards on the season, but Phil Mafah has earned co-starter status with 6.6 yards per carry and a team-high three rushing TDs. Beaux Collins and Antonio Williams lead Clemson's WR corps as top targets for QB Cade Klubnik, who's thrown for eight TDs and two picks on the season. 

When the Seminoles have the ball, keep an eye on FSU WR Keon Coleman. He's already grabbed four TD receptions and averages 14.2 yards per catch. 

Prediction: Clemson is one loss away from elimination in the College Football Playoff. Travis vs. Klubnik and the passing games are a wash for us, but the Tigers rate the edge on the ground and on defense. Take Clemson in a close ACC contest that goes down to the wire.  

Our pick: Clemson

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