Iowa State vs TCU Prediction, Odds, Lines, Spread, and Picks

Iowa State Cyclones are 9.5-point underdogs against the 11-0 TCU Horned Frogs. The Cyclone's lost at Texas Tech 14-10 and the Horns beat Baylor 29-28. In their last 10 meetings, the Cyclons and Horneds have split the victories.

Iowa State plays TCU on Saturday, November 26 at 4:00 PM ET at Amon G. Carter in Fort Worth, Texas.

Iowa State has one of the top defenses in the nation. The Cyclones gave up 14 points in their previous game. TCU has been on a winning streak this season. They defeated Baylor Bears but didn't cover the spread. They rank eighth in points scored and eleventh in total yards. Kendre Miller has scored 14 touchdowns and rushed for 1188 yards for the Horned Frogs.

Iowa State and TCU are playing each other today. The Cyclones have lost five of their last six games. TCU is 6-1-0 against the spread in their recent games and is the favorite to win.