Baylor vs. Iowa State Prediction: Big 12 Play Opens With Key Matchup in Ames

Baylor and Iowa State are playing each other in the Big 12 this weekend. The winner of the game will be crowned the champion of Big12. Baylor has won two of last three meetings in this series. Iowa has not won in Ames since 2016. The game could be a potential preview of a Big Twelve Championship Game.

Baylor and Iowa State are playing in the Big 12.

Baylor will look to establish a rhythm on the ground with its running game. Richard Reese has already rushed for five touchdowns in the first three games of the season. Iowa State owns the top-rated defense among its conference mates. The Cyclones also haven't given up many points either.

Iowa State has the Big 12's eighth-best total offense at 415 yards per game. Baylor is the No. 3 defense in the conference, allowing just 290.3 yards a game this season. The defense had a good rebound game last week against Texas State. The Bears held the Bobcats to 268 yards and only 3.8 per snap.

Baylor and Iowa State are redefining the look of Big 12 football with hard-nosed defense and grinding together drives. Both teams scored in the 30s in their last two meetings. The home team has won the last four games.