Lakers vs. Trail Blazers odds, line, spread: 2022 NBA picks, Feb. 2 predictions from proven computer model

The Los Angeles Lakers take on the Portland Trail Blazers at 10:30 p.m. ET on Wednesday. Los Los Ales is favored by 3.5 points. The Lakers are 24-27 overall and 15-12 at home, while Portland is 21-30 overall, 7-17 on road. SportsLine's advanced computer model simulates every NBA game 10,000 times and has returned well over $10,00 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons.

SportsLine's computer model has picked the Los Angeles Lakers vs. Portland Trail Blazers. The model is also picking the 2022 NBA game.

Lakers lost to Atlanta Hawks 129-121 on Sunday. Malik Monk had a double-double on 33 points and 10 rebounds. Lakers finished their six-game road trip with a 2-4 record. LeBron James is out injured. Los Angeles has won four of its last five home games against Portland.

Portland is on a two-game losing streak and has dropped four of its last five games. Damian Lillard is out injured, while Cody Zeller and Larry Nance Jr. are injured. The team's current scoring leader is CJ McCollum, who is averaging 20.8 points per game. Norman Powell is scoring 18.4 points, and Anfernee Simons is adding 15.6 points.

The model simulates Lakers vs. Trail Blazers 10,000 times and it's leaning under. It also generated a point-spread pick that's hitting in almost 60 percent of simulations.