MLB Odds: Orioles vs. Rays prediction, odds, and pick

The 2022 season starts with an AL East rivalry between Baltimore Orioles and Tampa Bay Rays. The Orioles finished last year at 52-110, 48 games behind the AL Eastern lead. Tampa won the division last season and is aiming to repeat that feat this year. Shane McClanahan will start on the mound for the opening game.   The team has its sights set on winning the World Series. It's time to continue with our MLB odds series with a prediction and pick.

The Orioles are underdogs against the rival Rays in the season opener. John Means will start for the Orioles. He made 26 starts last year and won six games. It's his first Opening Day start. The O's are hoping to get some early runs on the board.

Rookie pitcher McClanahan will start for the Rays on Opening Day. The Rays have a lot of power in their lineup, including sluggers Wander Franco and Brandon Lowe. Franco is one of the most exciting players in baseball. Lowe is coming off a career-high 39 home runs.

The Rays will cover the spread and pick up their first win of the 2022 campaign against the Orioles. It's McClanahan's first Opening Day start.