MLB Odds: Tigers vs. Orioles prediction, odds, pick

Matt Manning will start for the Tigers. Jordan Lyles will take the mound for Baltimore. The Orioles are 5.5 games behind the Tampa Bay Rays and have a series against the Houston Astros coming up on Thursday.   The Tigers have suffered this year due to their hitting and their bullpen, but not because of their starting pitching. They could be a factor in the American League wild card race if they improve their pitching next year.

Tigers are 57-91, while the Orioles are 52-90. Detroit is 5-0 against the O's this year. The Tigers have not allowed a manufactured run to Baltimore this season. They have allowed three solo homers and one two-run homer in their five wins over Baltimore. Baltimore has only one hit with runners in scoring position against Detroit this this years. Gunnar Henderson's two run homer on Tuesday was the only run-producing hit for Baltimore against Tigers pitching in this series.

The Tigers are the favorite to beat the Orioles. The Orioles are 20 games better in the standings than the Tigers. Baltimore is going to pick up at least one win against Detroit this year.

The Orioles are running out of gas and Jordan Lyles is not pitching well. Detroit would win the series if they swept all six games in the 2022 head-to-head series.