NCAA Football Predictions: Week 1 Opening Line Report, Best Bets and Picks

The college football season is officially underway. There are only three ranked games in the first week: Georgia vs. Oregon, Notre Dame vs Ohio State and Arkansas vs Cincinnati. Doc's Sports offers college game picks for every game on its predictions page.

Cam's College 3 Best Bets are the opening line for the NCAA Football season.

Penn State is playing a Big Ten road opener against Purdue on Thursday at 8 pm EST. The teams have played 12 times since 2000, with 10 of the victories going to Penn State. In the most recent six games, Penn Staters are 6-0. Last meeting was on 05/10/2019 35-7.

Arizona and San Diego State are playing a rematch from last year's game. SanDiego State is playing their first home game in their new Snapdragon Stadium. The Aztecs are going to win by double digits.

San Diego State is favored to win the game against the Aztecs.

Liberty Flames are playing Southern Miss on Saturday at 7 p.m. EST. The Flames beat Southern Mississippi 56-35 in 2020. Liberty is coming off a great 2021 season, while SouthernMiss is off the 3-9 year.

Florida will cover vs No. 7 Utah and Oregon will beat Georgia. Arkansas will win against Cincinnati by double digits.