Ohio State vs Penn State Prediction, Odds, Spread and Picks

Ohio State and Penn State are Big Ten rivals. The game will be played on Saturday at 12 pm ET at Beaver Stadium. Ryan Day's Buckeyes have won five straight games in the series. Penn state won last week's game against Minnesota 45-17.

Ohio State is 15.5-point favorite against Penn State. The total for the game is 61.

Ohio State is undefeated and the 2nd-ranked team in the country. The team is led by Heisman trophy favorite CJ Stroud. Jaxson Smith-Njigba is expected to play. Ohio State's offense ranks 3rd in yards and 1st in points per game. Their defense dominated Iowa last week.

Sean Clifford was Big Ten offensive player of the week after throwing for 295 yards and four touchdowns in last week's win over Minnesota. Freshman running back Nicholas Singleton has been a revelation this season with 7 touchdowns and 6.8 yards per carry. Penn State's offense is back on the right track after an off-night versus Michigan. The Nittany Lions are ranked 77th in the nation in sacks per game.

Ohio State has won nine of the last 10 games against Penn State. The road team is 4-1 against the spread in the past five meetings.