Ohio State vs Penn State Odds, Picks & Predictions

The winner of the regular season finale between the Ohio State Buckeyes and Michigan will be the de facto Big Ten champion. Penn State might not roll over, but it's more likely to fight fire with fire.

Penn State is the one-loss team that plays Ohio State on Saturday, October 27. The Nittany Lions are two-touchdown underdogs.

Ohio State has the best offense in the country. The team ranks fourth in total offense and second in scoring offense. Penn State's defense is starting to show some cracks. However, head coach James Franklin will have his team up for this matchup and give Ohio State its best effort. The Nittany Lions should be able to put up 17-24 points at home and that'll be enough to send this one Over the number. It's better to bet the total than backing the NPennany lions as dogs.

DraftKings offers new users $5 bet and $200 in free bets. Ohio State and Penn State play each other on Saturday.

The line for this Big Ten battle is 15.5. James Franklin is 0-10 straight up in his last 10 matchups against Top 10 teams. Penn State is also 0.0-5 SU in the last five meetings against Ohio State. The Nittany Lions are 4-1 ATS in those games, losing by an average of 7 points and by never more than 13.

Ohio State has scored at least 49 points in all four of its conference games so far. The Over is 4-0 in those games. Penn State is giving up an average of 15.3 points per game in Big Ten play.

The Over is 5-0 in Ohio State's last five games overall and 4-1 in Penn State’s last four games against teams with a winning record.

Ohio State vs. Penn State is a college football game.