Penn State vs Ohio State betting line: No. 13 Lions a big underdog against No. 2 Buckeyes
No. 13 Penn State is a big underdog against No. 2 Ohio State. The Nittany Lions are 6-1 and playing in front of a home crowd. Ohio is unbeaten and favored by 15.5 points. Penn is 1-7 against Ohio and the Buckeyes have won nine of 10 games. This is the largest underdog setup for Penn. State since a 2021 visit to Ohio. It covered the spread against Minnesota 45-17 last Saturday. The game is at noon on Saturday at Beaver Stadium. If Ohio beat Penn, it would be the worst home loss for the N.S. Lions since 2020.