Pittsburgh vs. Tennessee: Prediction, pick, spread, football game odds, live stream, watch online, TV channel

Pittsburgh and Tennessee are playing each other in an early-season game on Saturday. Pitt won last year's game 41-34. Both teams won their season openers. Pittsburgh beat West Virginia 38-31. Tennessee beat Ball State 59-10.  Tennessee is seeking to build off a bowl appearance.

Pittsburgh and Tennessee are playing football. The Panthers' new offensive coordinator Frank Cignetti Jr. wants his team to play more run-oriented football this season. Pitt ran 62 offensive plays in its opener, while Tennessee ran 86.

Pittsburgh's staff is familiar with Tennessee quarterback Hooker. Hook played against the Panthers in 2019 and 2020 while at Virginia Tech. He transferred to Tennessee in 2021 and started last season as the Vols' backup.

Pittsburgh and Tennessee are playing a game dubbed "The Johnny Majors Classic" in honor of the former Pittsburgh and Tennesse coach. Major led the Panthers to the 1976 national title and coached Tennessee for 16 seasons. The teams played their first two meetings at Tennessee in 1980 and 1983.

Pittsburgh vs. Tennessee is live streaming on the Internet and on TV.

Pittsburgh Panthers and Tennessee Volunteers are playing each other in Week 2. Last season, Pittsburgh won the game 41-34. The Panthers scored plenty in their 38-31 victory over West Virginia. Tennessee has improved since last season's meeting. SportsLine's computer model has returned almost $3,500 in profit over the past six-plus seasons.