Sixers vs. Cavaliers prediction, odds, spread and total for Wednesday

Asbury Park
 

The Philadelphia 76ers (45-22, 2nd in Atlantic) start a three-game road trip as they take on the Cleveland Cavaliers (44-27, 2nd in Central) Wednesday at 7:30 p.m. at Rocket Mortgage Field House.

The Sixers are on a five-game winning streak with their most recent victory coming against the Wizards on Sunday.

The Cavaliers are coming off back-to-back road wins against the Hornets, including a 120-104 victory last night.

Here are my picks and predictions for this matchup between two Eastern Conference-bound playoff teams with odds powered by Tipico Sportsbook.

Sixers vs. Cavaliers Spread: Cavaliers +2.5 (-110)

On the second night of a back-to-back, Cavs star Donovan Mitchell is back in the lineup but will still be without Jarrett Allen for the third straight game.

Cleveland is 19-6-1 against the spread (ATS) in its last 26 games at home against an opponent with a winning record on the road.

The Sixers are 1-3-1 ATS in the prior five meetings and have failed to cover in four in the past six matchups in Cleveland.

With the Sixers' recent struggles in Cleveland, bet on the home underdog as I expect the Cavaliers to cover this small spread with Mitchell back.

Sixers vs. Cavaliers total: Under 223.5 points (-112)

Despite this being one of the lowest totals on the board, take the under, and here's why.

This matchup has been historically great to the under in the last few seasons at Rocket Mortgage Field House as it's 21-7 in the past 28 matchups in Cleveland.

Bet the under here. Both of these teams are top three in opponents' points per game this season and have gone under this total in seven of the prior 10 meetings.

Sixers vs. Cavaliers moneyline: Cavaliers (+120)

This is the third and final meeting between these two Eastern Conference powerhouses that should feature two relatively healthy squads. Each team has won on its home court with Philly winning the most recent matchup, 118-112, on Feb. 15.

Cleveland sports one of the best home records in the NBA, and with Mitchell back in the starting five, I'm betting on the Cavs to earn the victory for the eighth time in their last nine games at Rocket Mortgage Field House.

My Best Bets

Place a wager on the Cavaliers as a small underdog (+120), to cover the +2.5 spread (-110) and the under 223.5 total points scored at -112 on Tipico Sportsbook.