SMU vs. East Carolina odds, spread, time: 2023 college football predictions, Week 7 picks from proven model

The SMU Mustangs visit the East Carolina Pirates on Thursday night in a key American Athletic Conference football showdown. Kickoff is set for 7:30 p.m. ET from Bagwell Field at Dowdy-Ficklen Stadium in Greenville, N.C. 

The Mustangs are 12.5-point favorites and the over/under for total points scored is 49.5 in the latest college football odds from the SportsLine consensus for SMU vs. East Carolina. Before entering any SMU vs. East Carolina picks, you'll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

The model knows SMU sophomore quarterback Preston Stone helps power the Mustangs' offense, completing 84 of 160 passes (58.8%) for 1,191 yards and 11 touchdowns with five interceptions and a rating of 137.7. Stone has also rushed for a score on 29 carries for 68 yards (2.3 average). He has one 300-yard passing performance, completing 15 of 20 throws (75%) for 300 yards and five touchdowns in a 69-0 win over Prairie View A&M on Sept. 16.

It also is aware that East Carolina junior running back Rahjai Harris powers the Pirates' rushing attack. He has carried 57 times for 217 yards (3.8 average) and four touchdowns. In the loss to Appalachian State, he rushed 12 times for 56 yards and two scores. He also has three receptions for 22 yards and a TD.

The model has simulated SMU vs. East Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over on the posted total, and it also says one side of the spread hits over 50% of the time!