2022 Big Ten Championship Game picks, odds, line: Michigan vs. Purdue prediction, best bets from proven model

The Michigan Wolverines and Purdue Boilermakers are playing in the 2022 Big Ten Conference Championship Game on Saturday night at Lucas Oil Stadium in Indianapolis. Michigan leads the all-time series 45-14 and has won the last four meetings. The Wolverine are coming off a 45,23 win at Ohio State last weekend. Purdue secured the West Division title with a 30-16 come-from-behind win over Indiana.

The college football odds and betting lines for Michigan vs. Purdue are as follows: Michigan is favored by 16.5 points. The over/under is 52 points and the money line is $900.

2022 Big Ten Championship Game is on Saturday. Michigan is favored by 16.5 points. Purdue is 5-1 against the spread against a team with a winning record.

J.J McCarthy came up big against Ohio State last week. He completed 12 of 24 passes for 263 yards and three touchdowns. For the season, McCarthy has been solid, completing 177 of 271 passes (65.3%) for 2,215 yards, 17 touchdowns and two interceptions for a rating of 153.2. With leading rusher Blake Corum out for the rest of the year, Michigan has turned to sophomore Donovan Edwards. Edwards has rushed for 687 yards (7.5 average) and six scores this season.

Purdue won its final three games of the regular season to capture their first Big Ten West title in program history. Senior wide receiver Charlie Jones is the only Big League receiver since 2000 to have five games with at least 10 catches and 100 yards in a single season. Quarterback Aidan O'Connell has completed 63.7% of his passes on 288 of 452 passing for 3,124 yards and 22 touchdowns.

SportsLine's model is leaning Over on the total and has an against-the-spread pick that cashes in well over 60% of simulations.