TCU vs. Texas Tech prediction, odds, line: 2022 Week 10 college football picks, best bets from proven model

TCU is unbeaten on the season and is alone atop the Big 12 Conference standings. The Horned Frogs defeated West Virginia 41-31 last Saturday. Texas Tech is coming off a 45-17 loss to Baylor. Kickoff is at noon ET. TCU is 8.5-point favorites. SportsLine's advanced computer model simulates every FBS college football game 10,000 times. It has generated a profit of almost $3,00 for $100 players on its top-rated college Football picks against the spread.

SportsLine's computer model has selected TCU vs. Texas Tech as a winner. The model is also recommending a 69-point payout. TexasTech is 6-0 against the spread in their last six games following a straight-up loss. TCU is currently 6th in the league and 8th overall.

TCU vs. Texas Tech is a college football game. The Red Raiders are 6-0 against the spread in their last six games following a straight-up loss. TCU is 6.1-1 ATS in its last eight games overall.

Max Duggan is having a solid season. He has completed 149 of 221 passes for 2,212 yards and 22 touchdowns. Kendre Miller is third on the team in rushing with 851 yards. He also has caught nine passes with 74 yards for 8.2 average.

Texas Tech is deep at the quarterback position, but the Horned Frogs are not a lock to cover the Texas Tech vs. TCU spread. Red Raiders' quarterback Behren Morton has completed 89 of 158 passes for 1,038 yards, six touchdowns and six interceptions. Sophomore Donovan Smith has started four games, passing for over 300 yards in three of them and tossing seven touchdown passes as a starter. Senior Xavier White leads the receiving corps with 33 receptions for 454 yards (13.8 average) and three touchdowns.

SportsLine's model is leaning Over on the total and predicts 73 points for Texas Tech vs. TCU. One side of the spread hits in well over 60% of simulations.