Titans vs. Bills Week 2 picks and odds: Bet on Buffalo at home

Buffalo Bills host the Tennessee Titans on Monday night.

Buffalo plays its home opener on Monday Night Football against Tennessee.

The Bills are double-digit favourites against the Titans. Tennessee's offence struggled against New York Giants in the first game. Buffalo is coming off a lopsided 31-10 win against Los Angeles Rams. The Bills have covered the number in each of their last four home games. The team that earned the No. 1 seed in AFC a year ago is the Tennessee Titans, who are the current No 1.

Titans under 17.5 points (-113) is a bad bet. Buffalo held Los Angeles to 10 points last week and has had more time to prepare for this game. The Bills Mafia will be loud and Tannehill will have a hard time communicating with his rookie receivers.

Bills are at home against the Rams. The Bills outscored the Super Bowl champs 21-0 over the final two quarters. Tennessee led New York 13-5 at the half but lost the game 21 -20.