Tennessee Titans at Buffalo Bills betting preview: NFL Week 2 Monday Night Football odds, trends, pick

Buffalo Bills are 10-point favorites against Tennessee Titans in Monday Night Football. Last week, the Bills beat the defending champions the Los Angeles Rams in the first game of the regular season. The Titans lost to the New York Giants as 5½-points home favorites.

Tennessee Titans are playing at Buffalo Bills on Monday Night Football at 7 p.m. ET.

Tennessee Titans are playing Buffalo Bills on Monday Night Football. The point spread is 10.

Tennessee Titans and Buffalo Bills are playing on Monday Night Football. The money line is Bills -430, Titans +350.

Tennessee Titans are playing against Buffalo Bills on Monday Night Football. The Titans' rushing performance last week was concerning. Buffalo had an outstanding showing on both sides of the ball against the reigning Super Bowl champions. Bills covered the spread at home.   The game script demands an abundance of throwing the football. Ryan Tannehill's lack of chemistry with his receiving corps will keep the Titans from scoring. It's a good bet for the Bills to cover the odds.

Tennessee Titans are playing against Buffalo Bills on Monday Night Football. Bills are favored to win 34-13.