USC vs Colorado Prediction, Odds, Spread and Best Bets
USC Trojans are 34-point favorites against Colorado Buffaloes. The teams have met 15 times in the Pac-12 series with USC winning all 15 games. Colorado is 3-1 against the spread over the past four games and 7-4 ATS in last 12 games with the Trojan.
The game between USC and the Washington is scheduled for 9:30 pm ET on Friday, November 11. The weather forecast is calling for sunny skies, 2 mph wind and a temperature of 68 degrees.
The public is willing to bet on the Trojans. The public split on whether to back the over or the under. USC is the favorite at -34 on points. They are the co-ninth choice to win the Pac-12 Championship at +6000.
After a great start to the season, USC is 2-4 ATS. The team is losing points at an average of 38.3 points per game. USC's quarterback Caleb Williams is listed at +900 in the Heisman Trophy odds.
Colorado is ranked 128th out of 131 FBS schools in total defense. They allowed 483.2 yards per game and 49 touchdowns. Colorado beat Cal in their first game under Mike Sanford Jr. since then.
USC is going to win this game. However, history shows that they'll be struggling to cover the point spread. This is the largest spread on a USC-Colorado game since 2012. USC won that game 50-6.
