USC vs. Washington State prediction, odds, line: College football picks, Week 6 best bets from proven model

No. 6 USC Trojans host Washington State Cougars on Saturday at 7:30 p.m. ET. USC has won four of its five games by double digits this season. Washington state bounced back from its first loss of the season with a 28-9 win over California in Week 5. The Trojan are favored by 13 points in the latest Caesars Sportsbook odds.

USC is the favorite against Washington State. The game is set for Saturday. SportsLine's model has made its picks and CFB predictions.

USC vs. Washington State is a college football game. The line is USC -13. USC is favored by 66 points.

USC has won four of its five games this year by double digits. The Trojans have scored at least 40 points in four out of five of their games. They are coming off a 42-25 win over Arizona State last week. USC has beaten Washington State in 12 of the last 14 meetings.

USC is 5-0 and favored by at least 9.5 points in all four of its wins. The Trojans have a big game at No. 11 Utah next week. Washington State has covered the spread in four out of five games this season.

USC is favored by two points against Washington State. The model has simulated Washington vs. USC 10,000 times and it has picked the Under in almost 60% of simulations.