UTSA vs. MTSU prediction, odds, line: 2022 Week 5 college football picks, bets from proven computer model

UTSA Roadrunners (2-2) and the Middle Tennessee Blue Raiders (3-1) are playing each other on Friday night. Last week, the Roadrunner's offense had an offensive explosion, defeating Texas Southern 52-24. MTSU is on a three-game win streak. In Week 4, Mtsu upset Miami 45-31. SportsLine's proprietary computer model simulates every FBS college football game 10,000 times and has returned a profit of more than $3,100 for $100 players on its top-rated collegefootball picks.

UTSA and MTSU are playing a college football game on Saturday. The game is a betting favorite at 4.5 points. SportsLine's computer model has made its picks and CFB predictions.

UTSA vs. MTSU money line is UTSA -180, MtsU +152. Roadrunners are 5-1 ATS in their last six games on turf. Blue Raiders are also 5 -1 in last 6 games overall.

Frank Harris is sixth in the nation in passing yards (1,310) and has 10 passing touchdowns. De'Corian Clark is second in Conference USA in both receiving yards and receiving touchdowns (417 and 6). In his last outing, he reeled in nine passes for 217 yards with three touchdowns and is a reliable weapon.

Chase Cunningham is a poised and accurate quarterback. Jaylin Lane is first on the team in receiving yards (231) with a score. UTSA is the favorite. The game is scheduled for Saturday at 7 p.m.

SportsLine's computer model is leaning Under on the total and against the spread.